About test
Pharmacogenomics - key to personalised and safer treatment
Learn how your unique genetic makeup determines your tolerance to different drugs and discover the safest and most effective drugs with pharmacogenomic testing

What is pharmacogenomic (PGx) test?
Pharmacogenomic (drug tolerance) test analyzes changes in human genes that affect drug tolerance and efficacy.
Changes in the proteins involved in drug metabolism can increase the accumulation or elimination of the drug in the body. This can cause unwanted side effects and reduce the effectiveness of treatment. Often, the patient needs to be prescribed a higher or lower dose than usual, or choose a completely different drug. By performing a pharmacogenetic test and applying the results, the risk of unwanted side effects of drugs is reduced, because it allows to select the most appropriate drug and dose.
Our proposed test analyzes various genes and their inherited variations that control the production, activity and movement of proteins involved in 175 drugs metabolism throughout the body. According to the results of the pharmacogenetic test, your doctor receives information about which drugs are suitable for you, which will be ineffective or harmful, and what is the required dose of the drug.
Why should a pharmacogenetic test be performed?
Personalised
The test helps determine the most appropriate medications and their dosages based on your unique genetic makeup and provides knowledge about possible reactions to medications even before you start taking them.
Informative
Since the unchanging variations of the individual's genes are tested, there is no need to repeat the test again if the dosage recommendations of specific drugs change or if there is a need to prescribe a new drug.
Safe
The test reduces the risk of adverse reactions to drugs, because specific active ingredients of drugs that may not be suitable for your body are analyzed.
Simple
A venous blood sample is sufficient for detailed pharmacogenomic analysis.
Fast
It saves you time because the test reduces the number of trials and errors in finding the right drug for treatment.
Reliable
The test is carried out in a modern certified laboratory operating according to the requirements of ISO 15189:2023.
When is a pharmacogenomic test recommended?
Pharmacogenomic testing is useful for individuals:
- For those who have experienced unwanted drug-induced side effects;
- For whom the medicines prescribed by the doctor were not effective;
- For those taking several medications at the same time;
- Who have a family history of drug intolerance;
- Whose condition requires a particularly precise dose of the drug;
- For those interested in personalized medicine and wanting to learn more about their medication tolerance;
Analyzed Drugs
During the test, the body's response is analyzed and drug prescribing recommendations for these drug categories are provided*:
- azaathioprine
- belinostat
- belzutifan
- capecitabine
- celecoxib
- dabrafenib
- erdafitinib
- fluorouracil
- gefitinib
- irinotecan
- mercaptopurine
- nilotinib
- pazopanib
- peginterferon alfa-2a
- peginterferon alfa-2b
- rucaparib
- sacituzumab govitecan
- siponimod
- tacrolimus
- tamoxifen
- tegafur
- thioguanine
- chloroquine
- hydroxychloroquine
- primaquine
- tafenoquine
- abrocitinib
- amikacin
- dapsone
- flucytosine
- gentamicin
- tacrolimus
- amikacin
- flurbiprofen
- gentamicin
- kanamycin
- piroxicam
- tobramycin
- acenocoumarol
- avatrombopag
- clopidogrel
- phenprocoumon
- warfarin
- codeine
- flurbiprofen
- hydrocodone
- ivacaftor
- meclizine
- amitriptyline
- amoxapine
- amphetamine
- aripiprazole
- aripiprazole lauroxil
- articaine/epinephrine
- atomoxetine
- brexpiprazole
- brivaracetam
- bupivacaine
- carbamazepine
- cevimeline
- citalopram
- clobazam
- clomipramine
- clozapine
- codeine
- desflurane
- desipramine
- deutetrabenazine
- dextromethorphan/bupropion
- dextromethorphan /quinidine
- diazepam
- donepezil
- doxepin
- enflurane
- escitalopram
- fluoxetine
- fluvoxamine
- fosphenytoin
- galantamine
- haloperidol
- halothane
- iloperidone
- imipramine
- isoflurane
- lamotrigine
- lofexidine
- mepivacaine
- methoxyflurane
- nortriptyline
- oliceridine
- oxcarbazepine
- oxycodone
- oxymetazoline/tetracaine
- paroxetine
- perphenazine
- phenytoin
- pimozide
- pitolisant
- protriptyline
- quetiapine
- risperidone
- sertraline
- sevoflurane
- tetrabenazine
- tramadol
- trimipramine
- valbenazine
- venlafaxine
- viloxazine
- vortioxetine
- zuclopenthixol
- abacavir
- amikacin
- atazanavir
- ceftriaxone
- dapsone
- dolutegravir
- efavirenz
- flucytosine
- gentamicin
- kanamycin
- nalidixic acid
- nelfinavir
- nitrofurantoin
- plazomicin
- raltegravir
- ribavirin
- streptomycin
- tobramycin
- voriconazole
- allopurinol
- carisoprodol
- celecoxib
- flurbiprofen
- ibuprofen
- lesinurad
- lornoxicam
- meloxicam
- pegloticase
- piroxicam
- succinylcholine
- tenoxicam
- atorvastatin
- carvedilol
- dextromethorphan /quinidine
- flecainide
- fluvastatin
- ibuprofen
- lovastatin
- mavacamten
- metoprolol
- nebivolol
- pitavastatin
- pravastatin
- propafenone
- propranolol
- rosuvastatin
- simvastatin
- darifenacin
- fesoterodine
- flibanserin
- ibuprofen
- mirabegron
- tamsulosin
- tolterodine
- ascorbic acid
- chlorpropamide
- dexlansoprazole
- dronabinol
- eliglustat
- esomeprazole
- glimepiride
- glipizide
- glyburide
- kanamycin
- lansoprazole
- metoclopramide
- moviprep
- nateglinide
- omeprazole
- ondansetron
- pantoprazole
- paromomycin
- rabeprazole
- streptomycin
- sulfasalazine
- tolazamide
- tolbutamide
- tropisetron
- methylene blue
- rasburicase
- sodium ascorbate
- sodium nitrite
- tolbutamide
- toluidine blue
Since the pharmacogenomic database is constantly updated, the list of drugs may be longer than this list at the time of the test.
* According to the ATC (Anatomical Therapeutic Chemical) classification system.
Test results
The study results (in Lithuanian or English) are reported according to CPIC (Clinical Pharmacogenetics Implementation Consortium), DPWG (Dutch Pharmacogenetics Working Group) and FDA (U.S. Food and Drug Administration's recommendations regarding the suitability, dosage, and compatibility of certain medications.
All information provided in the test answer is intended only for your doctor, who will be able to choose the most suitable medication for you based on the results obtained.
Where can a pharmacogenomic test be performed?
Contact our laboratory using the provided contacts.
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